Researchers describe the first successful use of a human patient’s cloned infection-fighting T cells as the sole therapy to put an advanced solid-tumor cancer into long-term remission. A team led by Cassian Yee, M.D., reports these findings in the New England Journal of Medicine.

Yee and colleagues removed CD4+ T cells, a type of white blood cell, from a 52-year-old man whose Stage 4 melanoma had spread to a groin lymph node and to a lung. T cells specific to targeting the melanoma were then expanded vastly in the laboratory using modifications to existing methods. The lab-grown cells were then infused into the patient with no additional pre- or post-conditioning therapies, such as growth-factor or cytokine treatment. Two months later, PET and CT scans revealed no tumors. The patient remained disease free two years later, when he was last checked…

Yee cautioned that these results, presented in the journal’s “Brief Report” section, represent only one patient with a specific type of immune system whose tumor cells expressed a specific antigen. More studies are needed to confirm the effectiveness of the experimental T-cell therapy. If proven successful in more patients, Yee predicted this therapy could be used for the 25 percent of all late-stage melanoma patients who have the same immune-system type and tumor antigen.

Cripes! Even if a very specific set of circumstances are required, this could be the beginning of a dynamic new mode of treatment for cancers.




  1. god says:

    What – no xhristian concern over the souls of those cute little T-cells?

  2. it's just an expression says:

    Or it could be another of many multiple strains of medical smokescreens.

  3. the answer says:

    Science is my new religion. Stem Cells > Prayer and i’m looking out for #1

  4. god says:

    Carry over the essential standard for religion and be certain not to let reality or facts get in the way.

  5. Cinaedh says:

    dear god (so to speak),

    If reality or facts got in the way of anything humans do, it would be a vastly different world in which we live.

  6. Peachy says:

    Why is it that guys like this aren’t cheered within society far greater than the knuckleheads who have a talent to:

    a) Bounce a ball
    b) Throw a ball
    c) Hit a ball

    Why o Why does society reward sports over science!

    Peachy
    Crawling back under his rock

  7. Jopa says:

    I salute this Doctor.
    This is brilliant work.
    I smell a noble prize….
    🙂

  8. Calin says:

    #6
    I think it’s because it is easier for the common person to cheer something they understand but can’t do, as compared to something with which they can do neither.

    It’s easy to see the skill with which Tiger hits a golf ball, or how Payton completes a pass. Explain this T-cell procedure to the average person and they ask you what a T-cell is. They think cloning is something like what Dr. Evil did.

  9. Mister Mustard says:

    #’s 1, 3

    Jesus. Obviously you brainiacs flunked out of junior high biology. T cells are not the same thing as stem cells.

    Great application of Dvorak’s Law, though. The very first post started in with the “Xhristian” bashing.

    You Worshippers At The Altar of Dawkins are so fucking predictable. Story about HP printers? Bash the Christians. Story about WiMax? Bash the Christians. Story about Natali del Conte? Bash the Christians.

    You’re obsessed!

  10. blah blah blah says:

    Mustard –

    You beat me to it… nice way for the readers to start off Christian-bashing. Maybe Perkel was right in that Atheists really do think about God more than non-Atheists. These Secular Humanist followers must be getting more and more indoctrinated as Eideard didn’t even mention non-Atheists in his commentary.

    That being said, this is a neat development and looks like it could really go somewhere. I do have the same worry as chuck, though in that a patent system that allows genes to be patented, we may end up having to pay separate royalties for access to our own T-Cells aside from the cost of a procedure.

  11. Les says:

    I wished this was around last year. Lost my Dad to cancer 11 months ago today.

  12. deowll says:

    They were using T cells maybe as long as a decade ago. The thing is it worked sometimes and sometimes it seemed to do nothing nor was it used alone.

    Even at that I’d call it a great success but the industry didn’t make it available for wide use at that time.

    The new thing is this, “as the sole therapy to put an advanced solid-tumor cancer into long-term remission.”

    Its use as the sole therapy does suggest that they think they have a handle how to make this work every time at least with the right kind of tumor.

  13. god says:

    #10 – Pwned. Lamer.

  14. Daniel says:

    I wonder if this could be of any benefit for PWA’s or people with HIV.

    As somone with a whole whopping 10 cd4+ cells per cubic milliliter, it would sure be nice o have an immune system again. That way i wouldn’t hve the uncertainty of whether i’d be healthy one day and in the hospital th next.


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