Scientists have combined a normally inactive lidocaine derivative with capsaicin, the ‘heat’-generating ingredient in chili peppers, to produce pain-specific local anesthesia. When injected into rats, this combination completely blocked pain without interfering with either motor function or sensitivity to non-painful stimuli. The finding suggests an improved way to treat pain from childbirth and surgical procedures. It may also lead to new treatments to help the millions of Americans who suffer from chronic pain.

Yes, I live in a chile-exporting state. We think chiles can cure everything. Science just happens to be proving us correct.

The study used a combination of capsaicin — the substance that makes chili peppers hot — and a drug called QX-314. This combination exploits a characteristic unique to pain-sensing neurons, also called nociceptors, in order to block their activity without impairing signals from other cells. In contrast, most pain relievers used for surgical procedures block activity in all types of neurons. This can cause numbness, paralysis and other nervous system disturbances.

Researchers think this may be effective on incident-specific and surgical pain, perhaps even chronic pain. And itching.