A nanotechnologist has created the world’s smallest and most plentiful smiley, a tiny face measuring a few billionths of a metre across assembled from strands of DNA.

Dr Paul Rothemund at the California Institute of Technology can make 50 billion smileys, each a thousand times smaller than the diameter of a human hair, with his technique.

Rothemund has been working on flat, two-dimensional shapes but says that 3D structures in DNA should be quite feasible with this technique.

One application would be a nano-scale ‘cage’ in which pharmaceutical researchers, working on novel drugs, could sequester enzymes until they were ready for use in turning other proteins on and off.

Cool.



  1. Bill says:

    What does he do – knit them? The double helix look a little like yarn…

  2. Angel H. Wong says:

    That ain’t no smiley!

    That’s a frickin’ skull!

  3. Kent Goldings says:

    This is just cool.

  4. I wonder if walmart will sue, it a yellow smilly face, don’t they have a tradmark on that now. Sorry I am just being a jerk here. but.

  5. RTaylor says:

    It is a spooky looking thing.

  6. Don says:

    Jack o’Lantern!

  7. Dusan Maletic says:

    It’s not the Walmart,… MS is the one who have patented it for the Messenger…

  8. Awake says:

    That looks just plain evil.


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